HyperModules: identifying clinically and phenotypically significant network modules with disease mutations for biomarker discovery
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چکیده
منابع مشابه
HyperModules: identifying clinically and phenotypically significant network modules with disease mutations for biomarker discovery
SUMMARY Correlating disease mutations with clinical and phenotypic information such as drug response or patient survival is an important goal of personalized cancer genomics and a first step in biomarker discovery. HyperModules is a network search algorithm that finds frequently mutated gene modules with significant clinical or phenotypic signatures from biomolecular interaction networks. AVA...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2014
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btu172